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Posts Tagged ‘nanotech

Synthetic Biology

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http://www.genomeweb.com//node/959744?hq_e=el&hq_m=908479&hq_l=2&hq_v=dfe7ca028f

NEW YORK (GenomeWeb News) — Yale University has launched its Biodesign Institute focused on bringing together cell biologists with engineers for the discovery of systems and design principles uniting living and synthetic materials at the nano-scale…

The university said the institute’s work will focus on the creation of what [James] Rothman has called “natural machines,” or nano-machines capable of tasks ranging from functioning inside cells, to producing materials for tissue engineering, to carrying out programmed tasks as DNA robots…

The Biodesign Institute …campus, acquired from Bayer HealthCare in 2007, consists of 1.6 million square feet of research, office and warehouse space…

‘The institute will position Yale to be a world leader in several exciting areas, including the discovery and analysis of cellular nano-machines, synthetic biology, bio-inspired design of active materials and dynamic optical microscopy on the nanoscale,’…

Written by citizen2009

January 17, 2011 at 2:43 pm

Nano Spies?

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Gold, DNA Mix Could Result in Biological Nano Spies

Scientists use genetic material to develop gold nanostructures that could report on a cell’s inner workings in real time
By Jaya Jiwatram Posted 07.08.2008 at 1:21 pm 0 Comments
Nano Rush? A gold nanostructure tethered together with DNA could report information about changes at a cellular level. iStockphoto

Gold is valuable to many in copious quantities, but for a team of Duke University scientists, a sub-cellular amount was all that was needed to create a nanostructure which could potentially act as a tiny biological sensor. One which could penetrate individual cells and report back on a cell’s inner workings in real time.

But creating the nanostructure—a few thousandths the size of a living cell—wasn’t as simple. A team of materials engineers and chemists worked together using DNA to assemble the structure. Constructed to resemble a planet, the nanostructure, also named the “core-satellite,” has smaller moons tethered to it by strands of DNA, essential not only as glue but also as a biological component to recognize other molecules within a living organism. When faced with the right DNA molecules, the DNA tethers contract and expand and the satellites move in relation to the core, altering the optical properties of the structure. Since the structure is able to absorb and scatter light as the structure changes, researchers can tell what is happening at a molecular level by measuring color changes. Such measurements could provide essential information about cell processes to the medical and scientific fields.

The Duke University team is going to continue experimenting with pure metals and alloys to figure out a mix of components that will allow them to better detect results.

http://www.popsci.com/scitech/article/2008-07/gold-dna-mix-could-result-biological-nano-spies

Written by citizen2009

March 13, 2010 at 6:19 pm